Cancer in the uterine neck and human papilloma virus in women who visit the external gynecology consultation area

Cáncer en cuello uterino y virus del papiloma humano en mujeres que acuden al área de consulta externa de ginecología

  • Raúl Chávez Universidad Laica Eloy Alfaro de Manabí
  • Anaxímenes León Universidad del Zulia
  • Elisa Rodríguez Universidad Laica Eloy Alfaro de Manabí
Keywords: cervical cancer, human papillomavirus, women, hospital

Abstract

In order to determine the prevalence of cervical cancer and its association with the human papillomavirus (HPV), in women who attend the outpatient gynecology area of the SOLCA Manabí hospital, a descriptive cross-sectional study was carried out, whose census The population was 469 female patients aged between 18 and 61 years. The collection instrument was a card validated by groups of experts. The results detected three different genotypes of human papillomavirus: high risk en bloc of RA-HPV (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 66) (36.31%), high risk GET 16 (6.52%) and GET 18 (0.37%). Only 14, 30% present cancer in situ due to infection of the human papillomavirus with GET, of high oncogenic risk (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 66) in the same way, it is realized that the largest number of patients is located in low-grade lesions with 64.60% with a significant association between the risk factors associated with p <0.01 age, number of partners, sexual activity. It is concluded, the relevance of expanding the vaccine program against HPV infections of RA-HPV (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 66).

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References

Bansal D., Elmi A., Skariah S., Haddad P., Abu-Raddad L., J., Al Hamadi H., Mohamed-Nady N., Affifi N., Ghedira R., Hassen E., Al-Thani A., Al-Ansari A., & Sultan A. (2014). Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the State of Qatar. Journal of translational medicine, 12, 300.

Beddler G., Hernández-Solís S., Rueda-Gordillo F., Conde-Ferráez L., Gómez-Carballo J., González-Losa M. (2017). Epidemiología de la infección oral por VPH en sujetos jóvenes sanos. https:// dx.doi.org/10.4067/S0716-10182017000600557

Bedoya CH., Medina L., Espinosa M., Sánchez M., Parrales J., Molina D., Ibarra M.,Quimis M., España K., Parraga K., Cajas N., Orlando S., Robalino J., Chedraui P., Escobar S., Loja R., Ramirez C., Espinoza J., Sanchez S., Limia C., Aleman Y., Soto Y., Kouri V., Culasso A., Badano I. (2018). Molecular epidemiology and phylogenetic analysis of human papillomavirus infection in women with cervical lesions and cancer from the coastal region of Ecuado. Revista Argentina de Microbiologia 50 (2): 136-146.

Bosch X., Broker T., Forman D., Moscicki A., Gillison M., Doorbar J., Stern P., Stanley M., Arbyn M., Poljak M., Cuzick J., Castle P., Schiller J., Markowitz L., Fisher W., Canfell K., Denny L., Franco E., Steben M., Kane M., (2013). of ICO Monograph Comprehensive Control of HPV Infections and Related Diseases Vaccine Volume 30, Supplement 5, 2012 Comprehensive control of human papillomavirus infections and related diseases. https://doi.org/10.1016/j.vaccine.2013.10.003

Bruni L (2010). Prevalencia del virus del papiloma humano en 5 continentes: metanálisis de 1 millón de mujeres con hallazgos citológicos normales. J Infect Dis., 1789-1799.

Bruni L., Barrionuevo-Rosas L., Albero G., Serrano B. (2017). ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in the World. . Barcelona, Spain: Summary Report .

Bruni, L., Serrano, B., Bosch, X., & Castellsague, X. (2015). Vacuna frente al virus del pailoma humano .eficacia y seguridad. Enfermedades Infecciosas y Microbiologica Clinica, 342-354.

Chaturvedi A., Katki H., Hildesheim A., Rodríguez A., Quint W., Schiffman M., Van Doorn L., Porras C., Wacholder S., Gonzalez P., Sherman M., Herrero R., (2011). Human papillomavirus infection with multiple types: pattern of coinfection and risk of cervical disease. The Journal of infectious diseases 203 (7): 910–920.

Chauhan S., Jaggi M., Bell M., Verma M., Kumar D. (2009). Epidemiology of Human Papilloma Virus (HPV) in Cervical Mucosa. . Methods Mol Biol, 439-456.

Cobo,F., Ángel Concha. Marta Ortiz. (2009). Human Papillomavirus (HPV) Type Distribution in Females with Abnormal Cervical Cytology. A Correlation with Histological Study. . Open Virol J; 3: 60–66.

Cuzick J. (2008). Descripción general de las opciones basadas en el virus del papiloma humano y otras nuevas para el cribado del cáncer cervicouterino en países desarrollados y en desarrollo. Vaccines, 29-41

De Villiers EM, Fauquet C, Broker TR, Bernard HU, zur Hausen H (2004): Classification of papilloma viruses. Virology; 324: 17–27.

Flores C., Soriano D., Figueroa R., Gonzalo G., (2016).Genotipificación del virus del papiloma humano en mujeres que asisten a un hospital gineco-obstétrico de tercer nivel de la Ciudad de México. Revista chilena de ginecología ,81(5) p.381-387

García-Tamayo J., Molina J., Blasco-Olaetxea E. (2010). El virus del papiloma humano y el cáncer cervical: Una revisión de la historia actualizada sobre la investigación del cáncer del cuello uterino en Venezuela. Investigación Clínica, 51(2), 193-208. Recuperado en 16 de mayo de 2021, de http://ve.scielo.org/scielo.php?script=sci_art- text&pid=S0535-51332010000200004&lng=es&t- lng=es

Hui-Hui Xu (2018). Prevalence of human papillomavirus genotypes and relative risk of cervical cancer in China: a systematic review and meta-analysis. . Oncotarget. , 15386-15397

IARC. (2012). INCIDENCE AND MORTALITY CANCER IN SOUTH AMERICA. Washington: GLOBOCAN. Organización Mundial de la Salud . (2017). VIRUS DEL PAPILOMA HUMANO.

Organización Mundial de la Saud (2018). Papilomavirus humano PVH y cancer cervico uterino.

Orozco-Colín A., Carrillo-García A., Méndez-Tenorio A., Ponce-de-León S., Mohar A., Maldonado-Rodríguez R. (2010). Geographical variation in human papillomavirus prevalence in Mexican women with normal cytology. Int J Infect Dis; 14(12):e1082-e1087.

Romero-Morelos (2017). Genotipado de la humana virus de papiloma en un grupo de mujeres mexicanas tratadas en un hospital altamente especializado: Las infecciones múltiples y su potencial trascendencia en el programa de vacunación actual. Revista Salcedo M, Med Clin (Barc). 287- 292.

Samimi S., Mody R., Goodman S., Luna E., Armylagos D., Schwartz M., Mody D., Ge Y. (2018). Do Infection Patterns of Human Papillomavirus Affect the Cytologic Detection of High-Grade Cervical Lesions on Papanicolaou Tests?. Archives of pathology & laboratory medicine, 142(3), 347–352.

Sanabria J. (2009). Virus del Papiloma humano. Revista de Ciencias Médicas de Pinar del Río, 13(4), 168-187. Recuperado en 23 de abril de 2021, de http://scielo.sld.cu/scielo.php?script=sci_arttex-&pid=S156131942009000400019&lng=s&tlng=e

Saraiya M., Unger E., Thompson T., Lynch C., Hernandez B., Lyu C., Steinau M., Watson M., Wilkinson E., Hopenhayn C., Copeland G., Cozen W., Peters E., Huang Y., Sabre M., Altekruse S., Goodman M., HPV Typing of Cancer Workgroup (2015). Evaluación estadounidense de los tipos de VPH en cánceres: implicaciones para las vacunas actuales y de 9 valencia contra el VPH. Revista del Instituto Nacional del Cáncer ,

Sudenga S., ShresthaS., (2013). Key considerations and current perspectives of epidemiological studies on human papillomavirus persistence, the intermediate phenotype to cervical cancer. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 17(4), e216–e220. https:// doi.org/10.1016/j.ijid.2012.12.027
Published
2021-10-09
How to Cite
Chávez , R., León, A., & Rodríguez , E. (2021). Cancer in the uterine neck and human papilloma virus in women who visit the external gynecology consultation area: Cáncer en cuello uterino y virus del papiloma humano en mujeres que acuden al área de consulta externa de ginecología. REDIELUZ, 11(1), 18-26. Retrieved from https://produccioncientifica.luz.edu.ve/index.php/redieluz/article/view/36917
Section
Health Sciences