Development of vaccines against COVID-19 in record time
Desarrollo de vacunas contra el COVID-19 en tiempo record
Keywords:
SARS-COV-2, COVID-19, vaccines
Abstract
The SARS-CoV-2 is responsible for the COVID-19 that has affected millions of people and deaths in the world, needed urgent vaccine for the entire population. In this regard, modern technology has allowed effective vaccine developed in different parts of the world such as the United States, Germany, United Kingdom, China, among others; to control the COVID-19 pandemic. In this review the characteristics of the vaccines reached phase III studies and are currently being applied in immunization schedules in the world population against COVID-19 detailing. There are doubts whether these vaccines created in record time produce permanent immunity or protection against mutations of the SARS-CoV-2 and long-term adverse effects.
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References
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Baden L, El Sahly H, Essink B, Kotloff K, Frey S, Novak R, y cols; COVE Study Group. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med 2021;384(5):403-416.
Voysey M, Clemens S, Madhi S, Weckx L, Folegatti P, Aley PK, y cols; Oxford COVID Vaccine Trial Group. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet. 2021;397(10269):99-111.
Logunov D, Dolzhikova I, Shcheblyakov D, Tukhvatulin A, Zubkova O, Dzharullaeva A, y cols; Gam-COVID-Vac Vaccine Trial Group. Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia. Lancet 2021;397(10275):671-681.
Bos R, Rutten L, van der Lubbe J, Bakkers M, Hardenberg G, Wegmann F, Zuijdgeest D, y cols. Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses. NPJ Vaccines 2020;5:91. doi: 10.1038/s41541-020-00243-x.
Keech C, Albert G, Cho I, Robertson A, Reed P, Neal S, y cols. Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine. N Engl J Med. 2020;383(24):2320-2332.
Zhang Y, Zeng G, Pan H, Li C, Hu Y, Chu K, y cols. Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial. Lancet Infect Dis 2021;21(2):181-192.
Zhu F, Guan X, Li Y, Huang J, Jiang T, Hou L, Li J, y cols. Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet 2020;396(10249):479-488.
Diken M, Kranz L, Kreiter S, Sahin U. mRNA: A versatile molecule for cancer vaccines. Curr. Issues Mol. Biol. 2017, 22,113-128.
Oliver S, Gargano J, Marin M, Wallace M, Curran K, Chamberland M, y cols. The Advisory Committee on Immunization Practices' Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine - United States, December 2020. MMWR Morb Mortal Wkly Rep. 2020;69(50):1922-1924.
CDC COVID-19 Response Team; Food and Drug Administration. Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine - United States, December 14-23, 2020. MMWR Morb Mortal Wkly Rep. 2021;70(2):46-51.
Corbett K, Edwards D, Leist S, Abiona O, Boyoglu S y cols. SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness. Nature 2020, 586, 567–571
CDC COVID-19 Response Team; Food and Drug Administration. Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Moderna COVID-19 Vaccine - United States, December 21, 2020-January 10, 2021. MMWR Morb Mortal Wkly Rep. 2021;70(4):125-129.
Knoll MD, Wonodi C. Oxford-AstraZeneca COVID-19 vaccine efficacy. Lancet. 2021;397(10269):72-74.
Burki TK. The Russian vaccine for COVID-19. Lancet Respir Med. 2020;8(11):e85-e86.
Oliver S, Gargano J, Scobie H, Wallace M, Hadler S, Leung J, cols. The Advisory Committee on Immunization Practices' Interim Recommendation for Use of Janssen COVID-19 Vaccine - United States, February 2021. MMWR Morb Mortal Wkly Rep. 2021;70(9):329-332.
Published
2021-04-30
How to Cite
Mengual-Moreno, E., & Lizarzábal-García, M. (2021). Development of vaccines against COVID-19 in record time: Desarrollo de vacunas contra el COVID-19 en tiempo record. Revista Profesional HígadoSano, (20), 3-7. Retrieved from https://produccioncientifica.luz.edu.ve/index.php/higadosano/article/view/35785
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