
149Modified cancrinites as antibacterial agents
Rev. Téc. Ing. Univ. Zulia. Vol. 42, No. 3, 2019, Septiembre-Diciembre, pp. 104-151
Conclusions
Sodium-nitrate cancrinite and zeolite A were
ion-exchanged using: Ag+, Cu2+ and a Cu2+-Ag+ mixture. Ag+
and Cu2+-Ag+zeolites showed bactericidal action against
E. coli and P. aeruginosa using low Ag concentrations (5
mg) and short contact time (20 min). Ag+ binds to tissue
proteins and brings structural changes in the bacterial
cell membranes and cytosolic components leading to
cellular distortion and death. Cu2+ zeolites did not show
bactericidal activity, and they did not modify the growth of
the reference bacterial cultures. Cu is a bacterial nutrient,
required in cellular biochemistry of bacteria and in small
quantities it acts as a trace element in the metabolism
of the bacteria, the bactericidal effect was not observed
under the used experimental conditions.
Acknowledgment
Authors are grateful to CDCH-UC and FONACIT for its
for checking our article.
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